Laboratory No. 1 of NOKI of RA NAS of RA RA
” Design and synthesis of compounds regulating the activity of the cardiovascular system “
Head of the laboratory – Asya Agheki Aghekyan, candidate of chemical sciences
Phone: (+37410)-285-101
Email : aaghekyan@mail.ru
Researches are being carried out in the laboratory No. 1 of NOK of the National Academy of Sciences in the direction of creating new biologically active substances affecting the cardiovascular and central nervous systems, as well as having antibacterial, antioxidant and anti-inflammatory properties. Design and synthesis of substituted oxygen- and nitrogen-containing heterocyclic compounds, 1,4-benzodioxane and 4-spirosubstituted tetrahydroisoquinoline derivatives. Works are also being carried out in the field of non-cyclized counterparts of the latter. Researches are being carried out in the direction of obtaining heterocyclic annulated systems by introducing into their structure containing various pharmacophore groups.
substituted heterocycles: thiophene, pyrrolidine, thiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,2,4-triazole, and thienopyrimidine.
As a result of years of research, a number of potential drugs (fobufol, difalkin, emacor, beditin, mesedin) have been synthesized in the laboratory.
