ОДКГТК НОКИ no. 4 laboratories
Laboratory of Synthesis and Properties of Biologically Active Derivatives of Amino Acids and Peptides
The laboratory is engaged in the development and application of affordable and highly efficient synthesis methods for the creation of various amino acid and peptide derivatives to synthesize new biologically active compounds. Aiming at the creation of a pharmacy for the treatment or prevention of Alzheimer’s and Parkinson’s diseases, the anticholinesterase and antiradical activities of the synthesized compounds are also evaluated in the laboratory. Docking studies of the reaction of dehydroamino acid and peptide derivatives with acetyl- and butyrylcholinesterases, and studies aimed at revealing the relationship between chemical structure and biological properties are also carried out.
The composition of the laboratory
Vigen Oniki Topuzyan – Head of the Laboratory. RA NAS paper. member, doctor of chemical science, professor. E-mail: vtop@web.am
Stepan Grigori Grigoryan – senior scientific worker, doctor of chemical science. E-mail – grigstepan@yahoo com.
Armen Arami Hovhannisyan – senior scientist employee, candidate of chemical science. Email: armenarami@gmail.com
Zoya Meliki Farmazyan – senior scientist. employee, candidate of chemical science. Email: zoefa2000@yahoo.com
Suzanna Rudiki Tosunyan – science. Worker, candidate of chemical science. E-mail: syuzitos@mail.ru
Elizaveta Aleksanyan – graduate scientific worker. Email: aleksananliza@gmail.com
Eduard Apresi Hakobyan – Jr. science Worker. Email: ehakobyan@yhoo.com
Mari Lyova Atabekyan – graduate scientific worker. E-mail: atmari@yandex.ru
Ani Tigrani Makichyan – graduate student. E-mail: ani.makichyan@rau.am